What is CHX?

A Better Chlorhexidine

Chlorhexidine (CHX) has consistently proven itself as a safe and effective medical antimicrobial agent with nearly 60 years of proven clinical use.6 Since its discovery, scientific research has consistently demonstrated that its singular, pure form Chlorhexidine (CHX) is the active antimicrobial agent.7-9

Chlorhexidine is a highly effective antimicrobial with broad spectrum efficacy and quick kill.

Because chlorhexidine is a challenging chemical to work with, most products incorporate gluconic or acetic acid with chlorhexidine to create Chlorhexidine Digluconate (CHG) and Chlorhexidine Diacetate (CHA) respectively. Gluconic acid and acetic acid are additive and their inclusion has not been proven to offer any inherent antimicrobial benefits.8-13

That’s why the entrotech life sciences team developed a groundbreaking non-thermal, PCA-free manufacturing process that unlocks the true potential of pure chlorhexidine (CHX), thus, pursuing our mission of preventing more infections and creating better patient outcomes.

See Footnotes

6 Shepard, R.C. Kinmonth, J.B. Skin Preparation and Toweling in Prevention of Wound Infection. British Medical Journal. 1962; 2(5298): pp. 151-153

7 Davies, G.E. Francis, J. Martin, A.R. Rose, F.L. Swain, G. 1:6-DI-4- Chlorophenyldiguanidohexane (“Hibitane”*). Laboratory Investigation Of A New Antibacterial Agent Of High Potency. British Journal of Pharmacology and Chemotherapy. 1954; 9(2): pp. 192-6

8 Ascenzi, J.M. Handbook of disinfectants and antiseptics. 1996

9 McDonnell, G. Russell, A.D. Antiseptics and Disinfectants: Activity, Action, and Resistance. Clinical Microbiology Reviews. 1999; c12(1): pp.

10 Senior, N. Some observations of the formulation and properties of chlorhexidine. Journal of the Society of Cosmetic Chemists. 1973; 24(4): pp. 259-278

11 Block, S.S. Disinfection, sterilization, and preservation: Chlorhexidine. 5th ed. 2001; xxii: pp. 1481

12 Russell AD, Day MJ. Antibacterial activity of chlorhexidine. Journal of Hospital Infection. 1993; 25(4): pp. 229-38