Evidence and Efficacy

Overview

In Vitro

In-vitro log10 reduction antimicrobial efficacy testing was conducted on PrevahexCHX. A broad spectrum of microorganisms were tested and specifically selected due to their clinical relevance and prevalence as the cause of challenging Hospital Associated Infections (HAIs).

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Zone of Inhibition

PrevahexCHX is the only antimicrobial dressing on the market that can offer complete CHX antimicrobial protection throughout the transparent areas of the dressing. Zone of Inhibition testing (ZOI) demonstrated rapid bacteria elimination of multiple drug-resistant bacterial species both underneath and several millimeters beyond the perimeter of the dressing sample.

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Biocompatibility and Safety

To address concerns that antimicrobials can impair or slow down wound healing, studies were conducted to compare normal wound care and healing vs. the use of non-antimicrobial/traditional dressing. Our results showed normal wound healing observed.

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Physical Performance

PrevahexCHX products have been tested at the most fundamental levels to assure peak physical performance.

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Clinical Guidelines

Several clinical guidelines offer support and recommendations for the use of chlorhexidine-impregnated dressings to prevent and reduce incidence of catheter-related bloodstream infections (CRBSls) and surgical site infections (SSls).

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Studies

The Role of Antimicrobial Transparent Film Dressings in the Prevention of Catheter-Related Bloodstream Infections
Robert Garcia, BC, MT(ASCP), CIC, FAPIC

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In vitro Antimicrobial Effects of Chlorhexidine Diacetate versus Chlorhexidine Free Base Dressings.
George J. Holinga, PhD, and James E. McGuire, BS
entrotech life sciences inc., San Francisco, California

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Reaching One Peripheral Intravenous Catheter (PIVC) Per Patient Visit With Lean Multimodal Strategy: the PIV5Rights Bundle
Lee Steere, RN, CRNI, VA-BC and David M. O’Sullivan, PhD Hartford Hospital, Hartford, Connecticut

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